Refractory inflammatory hydrocephalus: A case report of a rare and complicated delayed sequelae following cerebral hemispherectomy surgery for epilepsy

Refractory inflammatory hydrocephalus: A case report of a rare and complicated delayed sequelae following cerebral hemispherectomy surgery for epilepsy

Blog Article

Hydrocephalus is a known complication following surgical resection of a cerebral hemisphere for refractory epilepsy, read more yet the pathological mechanism remains poorly understood.We present a case of refractory aseptic inflammatory hydrocephalus following cerebral hemispherectomy surgery for refractory epilepsy treated with a combination of cerebral spinal fluid (CSF) diversion and immunosuppression via life extension blueberry extract IL-1 receptor agonist, Anakinra.At 6 month follow up, the patient had returned to neurologic baseline, with improvement in school and physical therapy performance.Further investigation into the beneficial role of immunosuppressive therapy is needed to better understand the relationship between neuro-inflammation and improving outcomes following epilepsy surgery.